Musculoskeletal Biology

Faculty selected as IPREP mentors
Portrait of Matt Allen smiling at the camera.
Matt R. Allen, Ph.D. – Faculty Liaison
Professor of Anatomy, Cell Biology and Physiology
Tel: 317-274-1283
Email: matallen@iupui.edu
Office: MS5045Q
Our laboratory studies the tissue-level mechanisms responsible for musculoskeletal integrity in health and disease. We utilize numerous in vivo model systems to understand how disease and pharmaceutical intervention influence bone structure, cellular activity, tissue-level properties (such as mineralization, microdamage, collagen, hydration), and biomechanical properties. We study diseases/conditions such as osteoporosis, diabetes, osteoporosis imperfecta, chronic kidney disease, disuse, and aging using techniques such as imaging (CT, DXA, X-ray), histology (static and dynamic histomorphometry, microdamage), and mechanical testing (bending, compression, fatigue, reference point indentation). Our laboratory is funded by the NIH, NASA/NSBRI, and industry.
Post-Baccalaureate Research Education Program
Indiana University Indianapolis
Office of the Dean, School of Health & Human Sciences
1050 Wishard Blvd., Ste. 3000
Health Sciences Building (RG)
Indianapolis, IN 46202
Tel: 317-274-7447
Fax: 317-274-1024
Email: IPREP@iu.edu
Hours: Monday–Friday, 9:00 a.m.–4:00 p.m.